The Indian ace went down 2-6, 6-4, 4-6 to Japan's Akiko Morigami in the third round.
They lost to top seeded pair of Kveta Peschke and Maria Emilia Salermi in Cincinnati.
The Indian teenager will take on seventh seed Anna-Lena Groenefeld at the USD 170,000 Cincinnati Open.
While the year's final grand slam is just underway tennis fans have circled Sept. 8 when, if all goes to form, Nadal and Federer would meet to decide a place in the final.
The 26-year-old has not always handled the expectations placed on his shoulders after he won the Wimbledon junior title in 2008 with a game style uncannily like Federer's.
Four times now, twice at Wimbledon (2018, 2019) and at the US Open (2018, 2019) Serena Williams has come agonizingly close to that 24th Grand Slam only to fall at the final hurdle.
Rohan Bopanna and his Romanian partner Florin Mergea on Saturday made it to the final of the men's doubles event at the ATP World Tour Finals, in London, after registering a straight-set victory against Croatian Ivan Dodig and Marcelo Melo of Brazil.
Andre Agassi served up his traditional late-night feast at the U.S. Open on Monday, beating fellow American Robby Ginepri to move into the second round.
Top seed Lindsay Davenport had little difficulty advancing to the semi-finals at the Cincinnati Open on Friday.
The Australian registered a 6-4, 6-4 victory over Marat Safin in the quarter-finals of the Cincinnati Masters.
The Indian pair went down to Mark Knowles of Bahamas and Daniel Nestor of Canada at the ATP Tennis Masters in Cincinnati.
The Indian ace, who broke into the top-50 this week, is suffering from a stomach pull
Neha and Shikha lost in the final qualifying round of the women's doubles in the WTA tournament in Cincinnati.
Otto Warmbier, a University of Virginia student, sentenced to hard labour in prison for 15 years for stealing a political poster from a restricted floor in his hotel.
Former world number one Maria Sharapova avenged her US Open loss to Anastasija Sevastova with a 7-6(3), 5-7, 7-6(7) victory over the Latvian in the China Open first round on Saturday.
The good folks at National Geographic list out the most popular dishes that are as popular as the cities where they were invented.
Russian Daria Kasatkina will replace Sharapova in the main draw
After Nick Kyrgios, another Aussie involved in verbal volley as tempers flare in Ohio.
American great John McEnroe expects Roger Federer's sensational comeback season to continue in New York when the US Open kicks off on Monday.
The top seeds will take on seventh seeds Wayne Arthurs and Paul Hanley of Australia.
The ATP had fined him US$106,000 for failing to attend an interview. The world no 1 says he has been defamed and wants the fine dropped.
A summary of Thursday's play at the US Open.
American twins Bob and Mike Bryan added another accolade to their lengthy resume after taking the Shanghai Masters men's doubles title on Sunday to become the first pair to win all nine ATP World Tour Masters 1000 tournaments.
Swiss teenager Belinda Bencic capped a brilliant run to the Rogers Cup title on Sunday.
In the absence of an injured Yuki, a lot would depend on how the left-handed Prajnesh, who won a singles bronze medal at the Asian Games, performs.
Although Kyrgios dropped the opening set his level of play and interest rose dramatically after the pep talk and he swept the next three sets for a 4-6, 7-6(6), 6-3, 6-0 win.
'It's a humiliating time to be a human being.' It's a pity that the magnificent 17-year-old gorilla is dead. But it's not enough to hang our heads in shame or comfort ourselves with clicktivism, observes Bijoy Venugopal.
Roger Federer says he does not regret passing up the chance to topple great rival Rafael Nadal from the top of the world rankings at the ATP Finals in London this week.
Roger Federer kept up his sprint through the early rounds of the US Open on Thursday, steamrolling Steve Darcis of Belgium 6-1, 6-2, 6-1 to reach the third round of the year's final Grand Slam.
Summary of sports events and persons who made news on Monday
Former world number one Mats Wilander says only two things can keep Roger Federer from advancing - injury and distraction.
Rafa Nadal has returned to the Spain team as they seek to maintain their Davis Cup World Group status with a playoff tie against Ukraine in Madrid later this month, captain Alex Corretja said on Monday.
'He probably deserves a player that is probably more dedicated to the game than I am. He deserves a better athlete than me'
